Galvin JE, Tolea MI, Fargo KN, et al. Results from COG1201: A Proof-of-Concept Study of CT1812 in Participants with Mild-to-Moderate Dementia with Lewy Bodies. Slides presented at International Lewy Body Dementia Conference (ILBDC) 2025; Amsterdam, The Netherlands
Lizama BN, Keeling E, Cho E, et al. Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD). Sci Rep 15, 4256 (2025). https://doi.org/10.1038/s41598-025-87921-9
Donkor N, Kiehlbauch CC, Pappenhagen N, et al. Neuroprotective effect of Sigma-2 modulator CT2074 in a mouse model of ocular hypertension. Experimental Eye Research 249 (2024) 110143.
Lizama BN, Reaver A, Cho E, et al. Sigma-2 Receptor Modulators Alter Low-density Lipoprotein Receptor-mediated Lipid Trafficking in Retinal Pigmented Epithelial Cells. Poster presented at 2024 Keystone Conference on Dry Age-related Macular Degeneration; Pacific Grove, CA.
Caldwell J, Cho E, Caggiano AO, DiCaro V, Hamby ME.Characterization of Human iPSC-derived Neurons as an In Vitro Model to Investigate Sigma-2 Receptor Functions. Poster presented at 2024 Keystone Conference on Neurodegenerative Diseases.
Reaver A, Lizama BN, Caggiano AO, Hamby ME. Differentiated retinal pigment epithelial cells as a model for uncovering sigma-2 receptor functions and novel therapeutics for dry AMD. Poster presented at 2024 Association for Research in Vision & Ophthalmology.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, et al. Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease. Acta Neuropathol 147, 32 (2024).
Caldwell J, Cho E, Knezovich N, et al. A transcriptomic analysis to investigate the role of sigma-2 receptor modulators CT1812 and CT2168 in a mouse model of Alzheimer’s disease. Poster presented Nov 2023 at: Society for Neuroscience (SfN) annual meeting; Washington DC.
Cho E, Caldwell J, Pandey K, et al. A proteomic analysis to elucidate the role of sigma-2 receptor modulators CT1812 and CT2168 in a mouse model of Alzheimer’s disease. Poster presented Nov 2023 at: Society for Neuroscience (SfN) annual meeting; Washington DC.
Reaver AJ, Lizama BN, Pandey K, et al. Exploratory omics study reveals potential roles of sigma-2 receptor modulators in AAV1/2A53T-aSyn rat model of Parkinson’s disease. Poster presented Nov 2023 at: Society for Neuroscience (SfN) annual meeting; Washington DC.
Cognition Therapeutics assumes no responsibility for the content of third-party website. Neither does Cognition control, endorse or guarantee any aspect of your use of third-party sites. We encourage you to read and evaluate terms of use, privacy and other policies of the destination site as they may differ from Cognition’s policies.
Cognition Therapeutics assumes no responsibility for the content of third-party website. Neither does Cognition control, endorse or guarantee any aspect of your use of third-party sites. We encourage you to read and evaluate terms of use, privacy and other policies of the destination site as they may differ from Cognition’s policies.
Cognition Therapeutics assumes no responsibility for the content of third-party website. Neither does Cognition control, endorse or guarantee any aspect of your use of third-party sites. We encourage you to read and evaluate terms of use, privacy and other policies of the destination site as they may differ from Cognition’s policies.
Cognition Therapeutics assumes no responsibility for the content of third-party website. Neither does Cognition control, endorse or guarantee any aspect of your use of third-party sites. We encourage you to read and evaluate terms of use, privacy and other policies of the destination site as they may differ from Cognition’s policies.
Cognition Therapeutics assumes no responsibility for the content of third-party website. Neither does Cognition control, endorse or guarantee any aspect of your use of third-party sites. We encourage you to read and evaluate terms of use, privacy and other policies of the destination site as they may differ from Cognition’s policies.
